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Index > Protein center > Chrna4(Gene name) > Mouse
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  • Chrna4 (Gene name),
  • Neuronal acetylcholine receptor subunit alpha-4 (Protein name ),  ACHA4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Chrna4(Acra4);
    Protein name:
    Neuronal acetylcholine receptor subunit alpha-4;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-4 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly.
    Function:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    629
    Sequence:
    50:
    MEIGGSGAPP | PLLLLPLLLL | LGTGLLPASS | HIETRAHAEE | RLLKRLFSGY | 
    100:
    NKWSRPVANI | SDVVLVRFGL | SIAQLIDVDE | KNQMMTTNVW | VKQEWHDYKL | 
    150:
    RWDPGDYENV | TSIRIPSELI | WRPDIVLYNN | ADGDFAVTHL | TKAHLFYDGR | 
    200:
    VQWTPPAIYK | SSCSIDVTFF | PFDQQNCTMK | FGSWTYDKAK | IDLVSMHSRV | 
    250:
    DQLDFWESGE | WVIVDAVGTY | NTRKYECCAE | IYPDITYAFI | IRRLPLFYTI | 
    300:
    NLIIPCLLIS | CLTVLVFYLP | SECGEKVTLC | ISVLLSLTVF | LLLITEIIPS | 
    350:
    TSLVIPLIGE | YLLFTMIFVT | LSIVITVFVL | NVHHRSPRTH | TMPAWVRRVF | 
    400:
    LDIVPRLLFM | KRPSVVKDNC | RRLIESMHKM | ANAPRFWPEP | ESEPGILGDI | 
    450:
    CNQGLSPAPT | FCNRMDTAVE | TQPTCRSPSH | KVPDLKTSEV | EKASPCPSPG | 
    500:
    SCHPPNSSGA | PVLIKARSLS | VQHVPSSQEA | AEGSIRCRSR | SIQYCVSQDG | 
    550:
    AASLTESKPT | GSPASLKTRP | SQLPVSDQTS | PCKCTCKEPS | PVSPITVLKA | 
    600:
    GGTKAPPQHL | PLSPALTRAV | EGVQYIADHL | KAEDTDFSVK | EDWKYVAMVI | 
    629:
    DRIFLWMFII | VCLLGTVGLF | LPPWLAGMI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    E1913m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    E1913c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    E1913h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    E1913r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    U1913m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    U1913h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    U1913c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    U1913r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    P1913Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Polyclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    P1913Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Cat.:
    P1913Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Monoclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Monoclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Monoclonal Antibody for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Protein for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Protein for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Protein for Mouse Neuronal acetylcholine receptor subunit alpha-4
    Protein for Mouse Neuronal acetylcholine receptor subunit alpha-4

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    Precision
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    Linearity
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    References
    1. 1.
      "Long sleep and short sleep mice differ in nicotine-stimulated 86Rb+ efflux and alpha4 nicotinic receptor subunit cDNA sequence."
      Stitzel J.A. , Dobelis P. , Jimenez M. , Collins A.C.
      Pharmacogenetics11:331-339(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-529
      strain: Long sleep selected line.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Diencephalon.
      tissue: Hippocampus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    4. 4.
      "Promoter analysis of the neuronal nicotinic acetylcholine receptor alpha4 gene: methylation and expression of the transgene."
      Watanabe H. , Zoli M. , Changeux J.-P.
      Eur. J. Neurosci.10:2244-2253(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-27
    5. 5.
      "Expression of mouse nicotinic acetylcholine receptor genes in the developing thymus."
      Kuo Y.-P. , Lukas R.J.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 118-357
      strain: C57BL/6.
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